Drug reference
tolbutamide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Insulin secretagogues)
Mechanism of action
Initial effect is to increase beta-cell insulin secretion May also decrease rate of hepatic glucose production, increases insulin receptor sensitivity, and increases number of insulin receptors
Common side effects
- Hypoglycemia
- Agranulocytosis
- Aplastic anemia
- Dermatologic recations
- Hyponatremia
- Disulfiram-like reactions
Related conditions
Frequently asked questions
What drug class is tolbutamide?
tolbutamide belongs to: Endocrine.
How does tolbutamide work?
Initial effect is to increase beta-cell insulin secretion May also decrease rate of hepatic glucose production, increases insulin receptor sensitivity, and increases number of insulin receptors
What are the common side effects of tolbutamide?
Hypoglycemia, Agranulocytosis, Aplastic anemia, Dermatologic recations, Hyponatremia, Disulfiram-like reactions
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.