Drug interactions
aliskiren + enalapril (in diabetes)
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Renal impairment/hyperkalemia risk; contraindicated per label.
Mechanism of action
Dual RAAS blockade.
Clinical management
Contraindicated in diabetics; avoid in renal impairment.
References
Frequently asked questions
Can I take aliskiren with enalapril (in diabetes)?
The interaction is rated: Contraindicated. Renal impairment/hyperkalemia risk; contraindicated per label.
How serious is the interaction between aliskiren and enalapril (in diabetes)?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between aliskiren and enalapril (in diabetes) managed?
Contraindicated in diabetics; avoid in renal impairment.
Why do aliskiren and enalapril (in diabetes) interact?
Dual RAAS blockade.
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