Drug interactions

aminolevulinic acid + bicalutamide

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Moderate · Evidence level: Low

Oral aminolevulinic acid causes photosensitivity, and bicalutamide has been associated with photosensitivity reactions. Using them together may increase the risk of phototoxic skin injury.

Mechanism of action

Additive photosensitising effects.

Clinical management

Counsel on strict sun and bright indoor light avoidance for the period specified in the aminolevulinic acid labeling. Consider timing bicalutamide around the procedure if feasible.

Drug reference

Frequently asked questions

Can I take aminolevulinic acid with bicalutamide?

The interaction is rated: Moderate. Oral aminolevulinic acid causes photosensitivity, and bicalutamide has been associated with photosensitivity reactions. Using them together may increase the risk of phototoxic skin injury.

How serious is the interaction between aminolevulinic acid and bicalutamide?

The interaction is rated: Moderate. Evidence level: Low.

How is the interaction between aminolevulinic acid and bicalutamide managed?

Counsel on strict sun and bright indoor light avoidance for the period specified in the aminolevulinic acid labeling. Consider timing bicalutamide around the procedure if feasible.

Why do aminolevulinic acid and bicalutamide interact?

Additive photosensitising effects.

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