Drug interactions
aminolevulinic acid + indapamide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Indapamide may cause photosensitivity, and oral aminolevulinic acid induces transient photosensitivity. Together they may increase the likelihood of phototoxic skin reactions.
Mechanism of action
Additive photosensitizing effects through pharmacodynamic synergism.
Clinical management
Avoid other photosensitizers around the perioperative period of oral aminolevulinic acid and counsel on strict light protection. Consider temporarily withholding indapamide if feasible.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with indapamide?
The interaction is rated: Moderate. Indapamide may cause photosensitivity, and oral aminolevulinic acid induces transient photosensitivity. Together they may increase the likelihood of phototoxic skin reactions.
How serious is the interaction between aminolevulinic acid and indapamide?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and indapamide managed?
Avoid other photosensitizers around the perioperative period of oral aminolevulinic acid and counsel on strict light protection. Consider temporarily withholding indapamide if feasible.
Why do aminolevulinic acid and indapamide interact?
Additive photosensitizing effects through pharmacodynamic synergism.
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