Drug interactions

aminolevulinic acid + moxifloxacin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Moderate · Evidence level: Low

Oral aminolevulinic acid causes photosensitivity through protoporphyrin accumulation, and moxifloxacin is also phototoxic. Together they may increase the risk of skin phototoxic reactions after light exposure.

Mechanism of action

Additive phototoxicity from different mechanisms.

Clinical management

Avoid other phototoxic drugs in the perioperative period around aminolevulinic acid dosing, as labeled, and counsel on strict sun and bright-light protection.

Drug reference

Frequently asked questions

Can I take aminolevulinic acid with moxifloxacin?

The interaction is rated: Moderate. Oral aminolevulinic acid causes photosensitivity through protoporphyrin accumulation, and moxifloxacin is also phototoxic. Together they may increase the risk of skin phototoxic reactions after light exposure.

How serious is the interaction between aminolevulinic acid and moxifloxacin?

The interaction is rated: Moderate. Evidence level: Low.

How is the interaction between aminolevulinic acid and moxifloxacin managed?

Avoid other phototoxic drugs in the perioperative period around aminolevulinic acid dosing, as labeled, and counsel on strict sun and bright-light protection.

Why do aminolevulinic acid and moxifloxacin interact?

Additive phototoxicity from different mechanisms.

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