Drug interactions

aspirin + ginkgo biloba

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Moderate · Evidence level: Moderate

Ginkgo may enhance antiplatelet effects of aspirin, increasing bleeding risk.

Mechanism of action

Pharmacodynamic: Ginkgolides antagonize platelet-activating factor, adding to aspirin’s antiplatelet effect.

Clinical management

Avoid routine co-use if possible. If combined, monitor closely for bleeding; counsel patients. Discontinue ginkgo at least 3-7 days before surgery or invasive procedures.

References

  • Ginkgo: Drug Information — Lexicomp
  • Ginkgo biloba: Drug information — UpToDate
  • Aspirin and ginkgo Interactions — Drugs.com

Frequently asked questions

Can I take aspirin with ginkgo biloba?

The interaction is rated: Moderate. Ginkgo may enhance antiplatelet effects of aspirin, increasing bleeding risk.

How serious is the interaction between aspirin and ginkgo biloba?

The interaction is rated: Moderate. Evidence level: Moderate.

How is the interaction between aspirin and ginkgo biloba managed?

Avoid routine co-use if possible. If combined, monitor closely for bleeding; counsel patients. Discontinue ginkgo at least 3-7 days before surgery or invasive procedures.

Why do aspirin and ginkgo biloba interact?

Pharmacodynamic: Ginkgolides antagonize platelet-activating factor, adding to aspirin’s antiplatelet effect.

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