Drug interactions
atorvastatin + cyclosporine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ statin levels → myopathy risk.
Mechanism of action
CYP3A4/P-gp/OATP interactions.
Clinical management
Use lowest dose or non-interacting statin; monitor CK.
Drug reference
References
Frequently asked questions
Can I take atorvastatin with cyclosporine?
The interaction is rated: Major. ↑ statin levels → myopathy risk.
How serious is the interaction between atorvastatin and cyclosporine?
The interaction is rated: Major. Evidence level: High.
How is the interaction between atorvastatin and cyclosporine managed?
Use lowest dose or non-interacting statin; monitor CK.
Why do atorvastatin and cyclosporine interact?
CYP3A4/P-gp/OATP interactions.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.