Drug reference
hydroxyurea
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
The precise mechanism by which hydroxyurea produces its cytotoxic and cytoreductive effects is not known. However, various studies support the hypothesis that hydroxyurea causes an immediate inhibition of DNA synthesis by acting as a ribonucleotide reductase inhibitor, without interfering with the synthesis of ribonucleic acid or of protein.
Common side effects
- Neutropenia
- Infections
- Other infections
- Viral infections
- Bacterial infections
- Gastrointestinal disorders
Related conditions
Frequently asked questions
What drug class is hydroxyurea?
hydroxyurea belongs to: Miscellaneous.
How does hydroxyurea work?
The precise mechanism by which hydroxyurea produces its cytotoxic and cytoreductive effects is not known. However, various studies support the hypothesis that hydroxyurea causes an immediate inhibition of DNA synthesis by acting as a ribonucleotide reductase inhibitor, without interfering with the synthesis of ribonucleic acid or of protein.
What are the common side effects of hydroxyurea?
Neutropenia, Infections, Other infections, Viral infections, Bacterial infections, Gastrointestinal disorders
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