Drug interactions
aminolevulinic acid + amlodipine-hydrochlorothiazide-valsartan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Hydrochlorothiazide is photosensitizing and may add to phototoxicity from oral aminolevulinic acid used for surgical imaging. This raises the risk of skin and eye photoreactions.
Mechanism of action
Additive photosensitization.
Clinical management
Advise strict light protection of skin and eyes in the perioperative period. Consider holding hydrochlorothiazide around the procedure if appropriate.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with amlodipine-hydrochlorothiazide-valsartan?
The interaction is rated: Moderate. Hydrochlorothiazide is photosensitizing and may add to phototoxicity from oral aminolevulinic acid used for surgical imaging. This raises the risk of skin and eye photoreactions.
How serious is the interaction between aminolevulinic acid and amlodipine-hydrochlorothiazide-valsartan?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and amlodipine-hydrochlorothiazide-valsartan managed?
Advise strict light protection of skin and eyes in the perioperative period. Consider holding hydrochlorothiazide around the procedure if appropriate.
Why do aminolevulinic acid and amlodipine-hydrochlorothiazide-valsartan interact?
Additive photosensitization.
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