Drug interactions
aminolevulinic acid + azilsartan-chlorthalidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Chlorthalidone is photosensitizing and may add to the phototoxicity of oral aminolevulinic acid used for surgical visualization. This raises the risk of skin burns on light exposure.
Mechanism of action
Additive photosensitization from two phototoxic agents.
Clinical management
Avoid sun and bright light exposure for the period specified in aminolevulinic acid labeling. Consider withholding the diuretic perioperatively if feasible.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with azilsartan-chlorthalidone?
The interaction is rated: Moderate. Chlorthalidone is photosensitizing and may add to the phototoxicity of oral aminolevulinic acid used for surgical visualization. This raises the risk of skin burns on light exposure.
How serious is the interaction between aminolevulinic acid and azilsartan-chlorthalidone?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and azilsartan-chlorthalidone managed?
Avoid sun and bright light exposure for the period specified in aminolevulinic acid labeling. Consider withholding the diuretic perioperatively if feasible.
Why do aminolevulinic acid and azilsartan-chlorthalidone interact?
Additive photosensitization from two phototoxic agents.
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