Drug reference
azilsartan-chlorthalidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Combination(CVS))
Mechanism of action
Angiotensin II blocker; displaces angiotensin II from AT1 receptor and may lower blood pressure by antagonizing AT1-induced vasoconstriction, aldosterone release, catecholamine release, Chlorthalidone produces diuresis with increased excretion of sodium and chloride at the cortical diluting segment of the ascending limb of Henle’s loop
Common side effects
- Dizziness
- Fatigue
- Hypotension
- Syncope
Boxed warnings
- When pregnancy is detected, discontinue as soon as possible; drugs affecting renin-angiotensin system causing oligohydramnios, which may result in fetal injury and/or death
Contraindications
- Anuria Coadministration with aliskiren-containing products in patients with diabetes
Related conditions
Frequently asked questions
What drug class is azilsartan-chlorthalidone?
azilsartan-chlorthalidone belongs to: Cardiovascular.
How does azilsartan-chlorthalidone work?
Angiotensin II blocker; displaces angiotensin II from AT1 receptor and may lower blood pressure by antagonizing AT1-induced vasoconstriction, aldosterone release, catecholamine release, Chlorthalidone produces diuresis with increased excretion of sodium and chloride at the cortical diluting segment of the ascending limb of Henle’s loop
What are the common side effects of azilsartan-chlorthalidone?
Dizziness, Fatigue, Hypotension, Syncope
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