Drug interactions
aminolevulinic acid + eprosartan-hydrochlorothiazide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Hydrochlorothiazide is a recognized photosensitizer and aminolevulinic acid causes photosensitivity of skin and eyes. Use together may increase the risk of phototoxic reactions such as severe sunburn-like skin injury.
Mechanism of action
Additive photosensitizing effects of the two agents.
Clinical management
Where possible, avoid other photosensitizing drugs during the period of photosensitivity after aminolevulinic acid. Reinforce strict light protection and consider holding the thiazide temporarily if clinically acceptable.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with eprosartan-hydrochlorothiazide?
The interaction is rated: Moderate. Hydrochlorothiazide is a recognized photosensitizer and aminolevulinic acid causes photosensitivity of skin and eyes. Use together may increase the risk of phototoxic reactions such as severe sunburn-like skin injury.
How serious is the interaction between aminolevulinic acid and eprosartan-hydrochlorothiazide?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and eprosartan-hydrochlorothiazide managed?
Where possible, avoid other photosensitizing drugs during the period of photosensitivity after aminolevulinic acid. Reinforce strict light protection and consider holding the thiazide temporarily if clinically acceptable.
Why do aminolevulinic acid and eprosartan-hydrochlorothiazide interact?
Additive photosensitizing effects of the two agents.
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