Drug interactions
aminolevulinic acid + etodolac
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Oral aminolevulinic acid increases protoporphyrin-related photosensitivity, and additional phototoxic drugs may increase skin reactions. Etodolac has some reported photosensitivity potential. The concern is mostly theoretical and limited to the perioperative period.
Mechanism of action
Additive phototoxic potential from drugs that sensitize the skin to light.
Clinical management
Avoid giving other potentially phototoxic drugs for 24 hours after oral aminolevulinic acid where alternatives exist. Counsel the patient to protect skin and eyes from light exposure during that time.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with etodolac?
The interaction is rated: Moderate. Oral aminolevulinic acid increases protoporphyrin-related photosensitivity, and additional phototoxic drugs may increase skin reactions. Etodolac has some reported photosensitivity potential. The concern is mostly theoretical and limited to the perioperative period.
How serious is the interaction between aminolevulinic acid and etodolac?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and etodolac managed?
Avoid giving other potentially phototoxic drugs for 24 hours after oral aminolevulinic acid where alternatives exist. Counsel the patient to protect skin and eyes from light exposure during that time.
Why do aminolevulinic acid and etodolac interact?
Additive phototoxic potential from drugs that sensitize the skin to light.
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