Drug reference

etodolac

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (NSAIDs)

Mechanism of action

Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclo-oxygenase (COX) isoenzymes, COX-1 and COX-2. May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity.

Common side effects

  • Pruritus
  • Nervousness
  • Dyspepsia
  • Dizziness
  • Blurred vision
  • Depression

Contraindications

  • Perioperative pain associated with coronary artery bypass graft Previous allergic reactions or asthma after taking aspirin or other NSAIDs

Related conditions

Frequently asked questions

What drug class is etodolac?

etodolac belongs to: Musculoskeletal.

How does etodolac work?

Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclo-oxygenase (COX) isoenzymes, COX-1 and COX-2. May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity.

What are the common side effects of etodolac?

Pruritus, Nervousness, Dyspepsia, Dizziness, Blurred vision, Depression

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference