Drug interactions
aminolevulinic acid + fluphenazine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Oral aminolevulinic acid causes photosensitivity, and phenothiazines such as fluphenazine are also photosensitizing. Together they may increase the risk of phototoxic skin reactions.
Mechanism of action
Additive photosensitization.
Clinical management
Avoid other phototoxic drugs around aminolevulinic acid dosing as labeled, and counsel on strict sun and bright light protection.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with fluphenazine?
The interaction is rated: Moderate. Oral aminolevulinic acid causes photosensitivity, and phenothiazines such as fluphenazine are also photosensitizing. Together they may increase the risk of phototoxic skin reactions.
How serious is the interaction between aminolevulinic acid and fluphenazine?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and fluphenazine managed?
Avoid other phototoxic drugs around aminolevulinic acid dosing as labeled, and counsel on strict sun and bright light protection.
Why do aminolevulinic acid and fluphenazine interact?
Additive photosensitization.
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