Drug reference
fluphenazine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic)
Mechanism of action
Phenothiazine; antagonizes dopaminergic D1 and D2 receptors; depresses release of hypothalamic and hypophyseal hormones
Common side effects
- Confusion
- Akathisia
- Dyskinesia
- Weight gain
- Dystonia
- Decreased gag reflex
- Muscle stiffness
Known interactions (10)
- fluphenazine + pimozide Contraindicated
- amisulpride + fluphenazine Major
- cabergoline + fluphenazine Major
- fluphenazine + pramipexole Major
- fluphenazine + quinidine Major
- fluphenazine + ropinirole Major
- fluphenazine + sotalol Major
- dopamine + fluphenazine Moderate
- fluphenazine + indapamide Moderate
- fluphenazine + methyldopa Moderate
Related conditions
Frequently asked questions
What drug class is fluphenazine?
fluphenazine belongs to: Central Nervous System.
How does fluphenazine work?
Phenothiazine; antagonizes dopaminergic D1 and D2 receptors; depresses release of hypothalamic and hypophyseal hormones
What are the common side effects of fluphenazine?
Confusion, Akathisia, Dyskinesia, Weight gain, Dystonia, Decreased gag reflex, Muscle stiffness
Which drugs interact with fluphenazine?
pimozide, amisulpride, cabergoline, pramipexole, quinidine, ropinirole, sotalol, dopamine, indapamide, methyldopa
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.