Drug interactions

aminolevulinic acid + gemifloxacin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Moderate · Evidence level: Moderate

Oral aminolevulinic acid causes photosensitivity, and gemifloxacin can also cause phototoxic reactions. Using both increases the chance of skin phototoxicity after light exposure.

Mechanism of action

Additive photosensitizing effects of the two drugs.

Clinical management

Avoid giving other phototoxic drugs around the aminolevulinic acid dosing period and counsel the patient on strict sun and bright-light protection. Choose a non-phototoxic antibiotic when possible.

Drug reference

Frequently asked questions

Can I take aminolevulinic acid with gemifloxacin?

The interaction is rated: Moderate. Oral aminolevulinic acid causes photosensitivity, and gemifloxacin can also cause phototoxic reactions. Using both increases the chance of skin phototoxicity after light exposure.

How serious is the interaction between aminolevulinic acid and gemifloxacin?

The interaction is rated: Moderate. Evidence level: Moderate.

How is the interaction between aminolevulinic acid and gemifloxacin managed?

Avoid giving other phototoxic drugs around the aminolevulinic acid dosing period and counsel the patient on strict sun and bright-light protection. Choose a non-phototoxic antibiotic when possible.

Why do aminolevulinic acid and gemifloxacin interact?

Additive photosensitizing effects of the two drugs.

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