Drug reference
gemifloxacin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Quinolones)
Mechanism of action
Acts by inhibiting both DNA gyrase and topoisomerase IV, which are essential for bacterial growth. Because of this dual mechanism, MIC values remain in the susceptible range for some double mutants (eg, S pneumoniae)
Common side effects
- Rash
- Headache
- Nausea
- Transaminases increased
- Diarrhea
Contraindications
- All drugs or conditions that prolong QT interval Documented hypersensitivity to gemifloxacin or other fluoroquinolones
Known interactions (5)
- gemifloxacin + pimozide Contraindicated
- gemifloxacin + thioridazine Contraindicated
- dronedarone + gemifloxacin Major
- gemifloxacin + quinidine Major
- gemifloxacin + strontium ranelate Moderate
Related conditions
Frequently asked questions
What drug class is gemifloxacin?
gemifloxacin belongs to: Anti Bacterial.
How does gemifloxacin work?
Acts by inhibiting both DNA gyrase and topoisomerase IV, which are essential for bacterial growth. Because of this dual mechanism, MIC values remain in the susceptible range for some double mutants (eg, S pneumoniae)
What are the common side effects of gemifloxacin?
Rash, Headache, Nausea, Transaminases increased, Diarrhea
Which drugs interact with gemifloxacin?
pimozide, thioridazine, dronedarone, quinidine, strontium ranelate
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