Drug interactions
aminolevulinic acid + gliclazide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Oral aminolevulinic acid used for visualization in surgery causes transient photosensitivity. Gliclazide is a sulfonylurea that may rarely cause photosensitivity, which could add to the skin phototoxicity risk during the period after dosing.
Mechanism of action
Additive photosensitizing effects of the two drugs.
Clinical management
Keep the patient out of strong light, including sunlight and bright indoor light, for the period stated in the aminolevulinic acid labeling. Check skin for phototoxic reactions after the procedure.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with gliclazide?
The interaction is rated: Moderate. Oral aminolevulinic acid used for visualization in surgery causes transient photosensitivity. Gliclazide is a sulfonylurea that may rarely cause photosensitivity, which could add to the skin phototoxicity risk during the period after dosing.
How serious is the interaction between aminolevulinic acid and gliclazide?
The interaction is rated: Moderate. Evidence level: Low.
How is the interaction between aminolevulinic acid and gliclazide managed?
Keep the patient out of strong light, including sunlight and bright indoor light, for the period stated in the aminolevulinic acid labeling. Check skin for phototoxic reactions after the procedure.
Why do aminolevulinic acid and gliclazide interact?
Additive photosensitizing effects of the two drugs.
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