Drug interactions
aminolevulinic acid + levofloxacin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Oral aminolevulinic acid causes photosensitivity, and levofloxacin is also phototoxic. Using both increases the risk of skin phototoxic reactions after exposure to light.
Mechanism of action
Additive photosensitizing effects.
Clinical management
Avoid other phototoxic drugs for the period stated in the aminolevulinic acid labeling and counsel on strict sun and bright light protection. Consider delaying levofloxacin if clinically acceptable.
Drug reference
Frequently asked questions
Can I take aminolevulinic acid with levofloxacin?
The interaction is rated: Moderate. Oral aminolevulinic acid causes photosensitivity, and levofloxacin is also phototoxic. Using both increases the risk of skin phototoxic reactions after exposure to light.
How serious is the interaction between aminolevulinic acid and levofloxacin?
The interaction is rated: Moderate. Evidence level: Moderate.
How is the interaction between aminolevulinic acid and levofloxacin managed?
Avoid other phototoxic drugs for the period stated in the aminolevulinic acid labeling and counsel on strict sun and bright light protection. Consider delaying levofloxacin if clinically acceptable.
Why do aminolevulinic acid and levofloxacin interact?
Additive photosensitizing effects.
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