Drug reference
levofloxacin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Quinolones)
Mechanism of action
L-stereoisomer of parent compound ofloxacin; D-isomer form is inactive Inhibits DNA gyrase activity, which in turn promotes breakage of DNA strands Good monotherapy with extended coverage against Pseudomonas spp, as well as excellent activity against pneumococcus
Common side effects
- Insomnia
- Constipation
- Dizziness
- Headache
- Nausea
- Diarrhea
Contraindications
- Documented hypersensitivity
Known interactions (8)
- amiodarone + levofloxacin Major
- hydroxychloroquine + levofloxacin Major
- levofloxacin + ondansetron Major
- aluminum hydroxide/magnesium hydroxide + levofloxacin Moderate
- fluconazole + levofloxacin Moderate
- gliclazide + levofloxacin Moderate
- levofloxacin + loperamide Moderate
- levofloxacin + warfarin Moderate
Related conditions
Frequently asked questions
What drug class is levofloxacin?
levofloxacin belongs to: Anti Bacterial.
How does levofloxacin work?
L-stereoisomer of parent compound ofloxacin; D-isomer form is inactive Inhibits DNA gyrase activity, which in turn promotes breakage of DNA strands Good monotherapy with extended coverage against Pseudomonas spp, as well as excellent activity against pneumococcus
What are the common side effects of levofloxacin?
Insomnia, Constipation, Dizziness, Headache, Nausea, Diarrhea
Which drugs interact with levofloxacin?
amiodarone, hydroxychloroquine, ondansetron, aluminum hydroxide/magnesium hydroxide, fluconazole, gliclazide, loperamide, warfarin
Full monographs, dosing and an interaction checker in the MediHelp app
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