Drug interactions
bosentan + cyclosporine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ bosentan and cyclosporine toxicity; contraindicated.
Mechanism of action
OATP/CYP interactions.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take bosentan with cyclosporine?
The interaction is rated: Contraindicated. ↑ bosentan and cyclosporine toxicity; contraindicated.
How serious is the interaction between bosentan and cyclosporine?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between bosentan and cyclosporine managed?
Contraindicated.
Why do bosentan and cyclosporine interact?
OATP/CYP interactions.
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