Drug reference
bosentan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
Competitive antagonist of endothelin-1; blocks endothelin receptors on vascular endothelium and smooth muscle resulting in inhibition of vasoconstriction
Common side effects
- Nasopharyngitis
- Headache
- Flushing
- edema
- Hgb decreased; >1 g/dL
- upper respiratory tract infection.
Known interactions (1)
- bosentan + cyclosporine Contraindicated
Related conditions
Frequently asked questions
What drug class is bosentan?
bosentan belongs to: Miscellaneous.
How does bosentan work?
Competitive antagonist of endothelin-1; blocks endothelin receptors on vascular endothelium and smooth muscle resulting in inhibition of vasoconstriction
What are the common side effects of bosentan?
Nasopharyngitis, Headache, Flushing, edema, Hgb decreased; >1 g/dL, upper respiratory tract infection.
Which drugs interact with bosentan?
cyclosporine
Full monographs, dosing and an interaction checker in the MediHelp app
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