Drug reference

balsalazide

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Gastrointestinal Tract (Azo Compounds)

Mechanism of action

Metabolized to mesalamine by intestinal flora Mesalamine (5-aminosalicylic acid) has anti-inflammatory effect; active component of sulfasalazine, specific MOA unknown; probably inhibits prostaglandin & leukotrienes synthesis & release in colon.

Common side effects

  • Vomiting
  • Headache
  • Abdominal pain

Contraindications

  • Hypersensitivity to salicylates, balsalazide, mesalamine

Known interactions (93)

Related conditions

Frequently asked questions

What drug class is balsalazide?

balsalazide belongs to: Gastrointestinal Tract.

How does balsalazide work?

Metabolized to mesalamine by intestinal flora Mesalamine (5-aminosalicylic acid) has anti-inflammatory effect; active component of sulfasalazine, specific MOA unknown; probably inhibits prostaglandin & leukotrienes synthesis & release in colon.

What are the common side effects of balsalazide?

Vomiting, Headache, Abdominal pain

Which drugs interact with balsalazide?

measles mumps rubella and varicella vaccine live, varicella virus vaccine live, aceclofenac, celecoxib, mesalamine, vadadustat, voclosporin, acetazolamide, acetylsalicylic acid, amlodipine-hydrochlorothiazide-valsartan, amlodipine-olmesartan-hydrochlorothiazide, aspirin, aspirin / citric acid / sodium bicarbonate, atenolol-chlorthalidone, azilsartan-chlorthalidone

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