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Drug interactions

Abrocitinib + Efavirenz

Severity: Moderate

Abrocitinib and Efavirenz: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Abrocitinib is cleared mainly by CYP2C19 and CYP2C9, and efavirenz affects these enzymes in a mixed way, with inhibition in some settings and induction of CYP3A4 and others.

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