Skip to content

Drug interactions

Acalabrutinib + Omeprazole

Severity: Major

Acalabrutinib and Omeprazole: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Acalabrutinib capsules dissolve poorly at higher gastric pH, so omeprazole can reduce its absorption and exposure.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to see why Acalabrutinib and Omeprazole interact, what to do about it, and the sources.

  • Mechanism of action
  • Clinical management
  • Evidence level

Free 14-day trial. No card needed.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in