Drug interactions
Acemetacin + Spironolactone
Severity: Major
Acemetacin and Spironolactone: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as acemetacin can reduce renal prostaglandin synthesis, causing potassium retention and reduced renal function.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Acemetacin and Spironolactone interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Spironolactone
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
