Drug interactions
Acetylsalicylic acid + Pemetrexed
Severity: Moderate
Acetylsalicylic acid and Pemetrexed: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs including aspirin at anti-inflammatory doses can reduce pemetrexed clearance and increase its toxicity, including myelosuppression, renal and gastrointestinal effects.
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Other interactions of Acetylsalicylic acid
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