Drug interactions
Acetylsalicylic acid + Sacubitril / valsartan
Severity: Moderate
Acetylsalicylic acid and Sacubitril / valsartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
At anti-inflammatory doses, aspirin can reduce renal prostaglandin synthesis, which may worsen renal function and blunt the antihypertensive effect of sacubitril/valsartan.
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Other interactions of Acetylsalicylic acid
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