Drug interactions
Acetylsalicylic acid + Spironolactone
Severity: Moderate
Acetylsalicylic acid and Spironolactone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aspirin, especially at higher doses, can reduce the diuretic and natriuretic effect of spironolactone.
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Other interactions of Acetylsalicylic acid
Other interactions of Spironolactone
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