Drug interactions
Adagrasib + Flecainide
Severity: Major
Adagrasib and Flecainide: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Adagrasib prolongs the QT interval and inhibits CYP3A4 and CYP2D6, and flecainide is a CYP2D6 substrate with a narrow therapeutic index and proarrhythmic potential.
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Other interactions of Flecainide
Other interactions of Adagrasib
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