Drug interactions
Adagrasib + Warfarin
Severity: Major
Adagrasib and Warfarin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Adagrasib inhibits CYP3A4 and CYP2C9, both of which contribute to warfarin metabolism, so warfarin exposure and INR may rise.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Adagrasib and Warfarin interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Warfarin
Other interactions of Adagrasib
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.