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Drug interactions

Ado-trastuzumab + Trastuzumab deruxtecan

Severity: Major

Ado-trastuzumab and Trastuzumab deruxtecan: major interaction.

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For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both are HER2-directed antibody-drug conjugates with cytotoxic payloads that cause myelosuppression, interstitial lung disease and cardiac toxicity.

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