Drug interactions
Agomelatine + Fluvoxamine
Severity: Contraindicated
Agomelatine and Fluvoxamine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluvoxamine strongly inhibits CYP1A2, the main route of agomelatine metabolism, causing a very large rise in agomelatine exposure.
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Other interactions of Agomelatine
Other interactions of Fluvoxamine
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