Drug interactions
Amiloride + Tolfenamic acid
Severity: Major
Amiloride and Tolfenamic acid: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as tolfenamic acid reduce renal prostaglandin synthesis, which lowers renin and aldosterone and impairs potassium excretion.
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Other interactions of Amiloride
Other interactions of Tolfenamic acid
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