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Drug interactions

5-htp + Maprotiline

Severity: Moderate

5-htp and Maprotiline: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

5-HTP is a serotonin precursor, and combining it with an antidepressant that raises synaptic serotonin and norepinephrine may increase the risk of serotonin toxicity.

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