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Drug interactions

Acalabrutinib + Esomeprazole

Severity: Major

Acalabrutinib and Esomeprazole: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Esomeprazole can substantially lower absorption of acalabrutinib tablets or capsules, which may weaken its anticancer effect.

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