Drug reference
esomeprazole
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Proton Pump Inhibitors)
Mechanism of action
PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion. Relative Potency: 1.6.
Common side effects
- Indigestion
- Flatulence
- Headache
- Nausea
- Abdominal pain
Contraindications
- Hypersensitivity to esomeprazole or other proton pump inhibitors (PPIs) Patients receiving rilpivirine- containing products
Known interactions (3)
- clopidogrel + esomeprazole Major
- esomeprazole + Levothyroxine Moderate
- esomeprazole + Sulpiride Moderate
Related conditions
Frequently asked questions
What drug class is esomeprazole?
esomeprazole belongs to: Gastrointestinal Tract.
How does esomeprazole work?
PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion. Relative Potency: 1.6.
What are the common side effects of esomeprazole?
Indigestion, Flatulence, Headache, Nausea, Abdominal pain
Which drugs interact with esomeprazole?
clopidogrel, Levothyroxine, Sulpiride
Full monographs, dosing and an interaction checker in the MediHelp app
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