Drug interactions
Acalabrutinib + Itraconazole
Severity: Major
Acalabrutinib and Itraconazole: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Itraconazole markedly increases acalabrutinib exposure, which may increase adverse effects such as bleeding, infections, cytopenias and atrial arrhythmias.
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Other interactions of Itraconazole
Other interactions of Acalabrutinib
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