Drug interactions
Acetazolamide + Aspirin / citric acid / sodium bicarbonate
Severity: Major
Acetazolamide and Aspirin / citric acid / sodium bicarbonate: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Acetazolamide can increase salicylate penetration into the brain and reduce its renal clearance, risking salicylate toxicity such as tinnitus, confusion and acidosis.
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Other interactions of Acetazolamide
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