Drug interactions
Acetylsalicylic acid + Indomethacin
Severity: Major
Acetylsalicylic acid and Indomethacin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining aspirin with indomethacin increases the risk of gastrointestinal ulceration and bleeding without added benefit.
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Other interactions of Acetylsalicylic acid
Other interactions of Indomethacin
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