Drug interactions
Acetylsalicylic acid + Metolazone
Severity: Moderate
Acetylsalicylic acid and Metolazone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose aspirin can reduce the diuretic and antihypertensive effectiveness of metolazone and may impair renal function in volume-depleted patients.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Acetylsalicylic acid and Metolazone interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Acetylsalicylic acid
Other interactions of Metolazone
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
