Drug reference
metolazone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Diuretics)
Mechanism of action
Inhibits reabsorption of sodium in distal tubules, causing increased excretion of water and of sodium, potassium, and hydrogen ions
Common side effects
- Dizziness
- Drowsiness
- Chest pain
- Depression
- Electrolyte abnormalities
- Glucosuria
Contraindications
- Documented hypersensitivity to metolazone or sulfonamides Anuria Hepatic coma or precoma
Known interactions (1)
- isocarboxazid + metolazone Moderate
Related conditions
Frequently asked questions
What drug class is metolazone?
metolazone belongs to: Cardiovascular.
How does metolazone work?
Inhibits reabsorption of sodium in distal tubules, causing increased excretion of water and of sodium, potassium, and hydrogen ions
What are the common side effects of metolazone?
Dizziness, Drowsiness, Chest pain, Depression, Electrolyte abnormalities, Glucosuria
Which drugs interact with metolazone?
isocarboxazid
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