Drug interactions
Acetylsalicylic acid + Valproic acid
Severity: Moderate
Acetylsalicylic acid and Valproic acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aspirin can raise the free fraction of valproic acid and may reduce its clearance, increasing the risk of valproate toxicity.
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Other interactions of Acetylsalicylic acid
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