Drug reference
valproic acid
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Epileptic Drugs)
Mechanism of action
May increase levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in brain; may enhance or mimic action of GABA at postsynaptic receptor sites; may also inhibit sodium and calcium channels
Common side effects
- Alopecia
- Asthenia
- Tremors
- Headache
- Nausea
- Thrombocytopenia
- Increased bleeding time
Known interactions (5)
- Lamotrigine + valproic acid Major
- escitalopram + valproic acid Moderate
- fenofibrate + valproic acid Moderate
- Fluvoxamine + valproic acid Moderate
- Methylphenidate + valproic acid Moderate
Related conditions
Frequently asked questions
What drug class is valproic acid?
valproic acid belongs to: Central Nervous System.
How does valproic acid work?
May increase levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in brain; may enhance or mimic action of GABA at postsynaptic receptor sites; may also inhibit sodium and calcium channels
What are the common side effects of valproic acid?
Alopecia, Asthenia, Tremors, Headache, Nausea, Thrombocytopenia, Increased bleeding time
Which drugs interact with valproic acid?
Lamotrigine, escitalopram, fenofibrate, Fluvoxamine, Methylphenidate
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