Drug interactions
Adagrasib + Carbamazepine
Severity: Major
Adagrasib and Carbamazepine: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbamazepine may reduce adagrasib exposure and efficacy, while adagrasib, a CYP3A4 inhibitor, may raise carbamazepine levels and cause toxicity such as dizziness, ataxia and diplopia.
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Other interactions of Carbamazepine
Other interactions of Adagrasib
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