Drug reference
carbamazepine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Epileptic Drugs)
Mechanism of action
Stabilizes inactivated state of sodium channels, thereby making neurons less excitable May reduce activity of nucleus ventralis of the thalamus or decrease synaptic transmission or summation of temporal stimulation leading to neuronal discharge
Common side effects
- Dry mouth
- Dizziness
- Vomiting
- Drowsiness
- Nausea
- Ataxia
Known interactions (30)
- carbamazepine + isocarboxazid Contraindicated
- carbamazepine + lorlatinib Contraindicated
- carbamazepine + lurasidone Contraindicated
- carbamazepine + phenelzine Contraindicated
- carbamazepine + procarbazine Contraindicated
- carbamazepine + selegiline Contraindicated
- carbamazepine + tranylcypromine Contraindicated
- apixaban + carbamazepine Major
- carbamazepine + cariprazine Major
- carbamazepine + clarithromycin Major
- carbamazepine + clozapine Major
- carbamazepine + efavirenz Major
- carbamazepine + erythromycin Major
- carbamazepine + ethinyl estradiol/levonorgestrel Major
- carbamazepine + irinotecan Major
- carbamazepine + ledipasvir-sofosbuvir Major
- carbamazepine + linezolid Major
- carbamazepine + lithium Major
- carbamazepine + lomitapide Major
- carbamazepine + nevirapine Major
- carbamazepine + oral contraceptives Major
- carbamazepine + pirfenidone Major
- carbamazepine + praziquantel Major
- carbamazepine + regorafenib Major
- carbamazepine + roflumilast Major
- carbamazepine + sofosbuvir-velpatasvir-voxilaprevir Major
- carbamazepine + tramadol Major
- carbamazepine + voriconazole Major
- carbamazepine + metronidazole Moderate
- carbamazepine + phenytoin Moderate
Related conditions
Frequently asked questions
What drug class is carbamazepine?
carbamazepine belongs to: Central Nervous System.
How does carbamazepine work?
Stabilizes inactivated state of sodium channels, thereby making neurons less excitable May reduce activity of nucleus ventralis of the thalamus or decrease synaptic transmission or summation of temporal stimulation leading to neuronal discharge
What are the common side effects of carbamazepine?
Dry mouth, Dizziness, Vomiting, Drowsiness, Nausea, Ataxia
Which drugs interact with carbamazepine?
isocarboxazid, lorlatinib, lurasidone, phenelzine, procarbazine, selegiline, tranylcypromine, apixaban, cariprazine, clarithromycin, clozapine, efavirenz, erythromycin, ethinyl estradiol/levonorgestrel, irinotecan
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