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Drug interactions

Adagrasib + Chloramphenicol

Severity: Major

Adagrasib and Chloramphenicol: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chloramphenicol may inhibit CYP3A4 and increase adagrasib exposure, potentially worsening QT prolongation, gastrointestinal and hepatic toxicity.

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