Drug reference
chloramphenicol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Miscellaneous(Anti Bacterial))
Mechanism of action
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; mainly bacteriostatic
Common side effects
- Rash
- Headache
- Nightmares
- Stomatitis
- Bone marrow suppression
- Gray syndrome
- Diarrhea
Contraindications
- Hypersensitivity Oral or topical use Bacterial prophylaxis Viral infections
Known interactions (17)
- chloramphenicol + warfarin Major
- alfuzosin + chloramphenicol Moderate
- aprepitant + chloramphenicol Moderate
- avanafil + chloramphenicol Moderate
- bromocriptine + chloramphenicol Moderate
- chloramphenicol + dutasteride-tamsulosin Moderate
- chloramphenicol + eletriptan Moderate
- chloramphenicol + eplerenone Moderate
- chloramphenicol + everolimus Moderate
- chloramphenicol + ibrutinib Moderate
- chloramphenicol + irinotecan Moderate
- chloramphenicol + lurasidone Moderate
- chloramphenicol + pazopanib Moderate
- chloramphenicol + ranolazine Moderate
- chloramphenicol + regorafenib Moderate
- chloramphenicol + tamsulosin Moderate
- chloramphenicol + tolvaptan Moderate
Related conditions
Frequently asked questions
What drug class is chloramphenicol?
chloramphenicol belongs to: Anti Bacterial.
How does chloramphenicol work?
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; mainly bacteriostatic
What are the common side effects of chloramphenicol?
Rash, Headache, Nightmares, Stomatitis, Bone marrow suppression, Gray syndrome, Diarrhea
Which drugs interact with chloramphenicol?
warfarin, alfuzosin, aprepitant, avanafil, bromocriptine, dutasteride-tamsulosin, eletriptan, eplerenone, everolimus, ibrutinib, irinotecan, lurasidone, pazopanib, ranolazine, regorafenib
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