Skip to content

Drug interactions

Ado-trastuzumab + Duvelisib

Severity: Moderate

Ado-trastuzumab and Duvelisib: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Duvelisib inhibits CYP3A4 and may raise DM1 exposure, potentially increasing toxicities such as thrombocytopenia, hepatotoxicity and neuropathy.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to see why Ado-trastuzumab and Duvelisib interact, what to do about it, and the sources.

  • Mechanism of action
  • Clinical management
  • Evidence level

Try Pro+ free for 14 days on the web. No card needed.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in